目的从虎杖中提取并分离蒽醌类成分大黄酸、大黄素、大黄酚和大黄素甲醚等。
Objective To extract and separate the anthraquinone compounds, such as rhein, emodin, chrysophanol, physcion, etc. from Rhizoma Polygoni Cuspidati.
天然大黄中大黄酚的含量较大，但其药效性比较单一，且活性远不及大黄酸强。
The content of Chrysophanol in natural Rhubarb is rich, but its effect is single, and activity is weaker than Rhein.
鉴于大黄酚具有大黄酸分子的基本母核，本文以植物中大黄酚为起始原料，经乙酰化、氧化和脱乙酰反应后制得大黄酸。
Seeing that Chrysophanol has the same basic parent structure with Rhein, Rhein was synthesized through acetylation, oxidation and deacetylation reaction taking Chrysophanol as raw material.
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