目的：观察针刺对局部脑缺血大鼠大脑皮层基质金属蛋白- 2 (MMP - 2)表达的影响。

Objective: To investigate the effects of acupuncture on the MMP-2 expression in cerebral cortex after permanent focal cerebral ischemia in rats.

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研究了不同部位脑组织的病理变化，主要改变为大脑皮层神经细胞呈局部缺血性改变，少数皮层下有软化坏死灶。

Pathological examination of the brain of the rabbits revealed that there was local ischemic change of the neurons of the cortex and necrosis in the subcortical region in a few of the rabbits.

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结论：SA可减轻大脑中动脉血栓所致局部脑缺血性损伤。

CONCLUSIONS: SA reduced focal cerebral ischemic injury induced by middle cerebral artery thrombosis.

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