Small t antigen could activate of the RNA polymerase gene promoter,as well as c-myc and c-fos oncogene transcription,repress cytoplasmic actin transcription and decrease cellular adhesion.
t抗原能反式激活RNA多聚酶基因的启动子,以及c-myc和c-fos癌基因转录,使细胞质肌动蛋白缺失和细胞粘附性下降。
参考来源 - SV40T抗原基因诱导可逆性永生化黑素细胞的生物学特征评价·2,447,543篇论文数据，部分数据来源于NoteExpress
逆转录多聚酶链反应检测间质胶原酶及金属蛋白酶组织抑制因子- 1基因表达水平。
The gene expression levels for interstitial collagenase and tissue inhibitor of metallo-proteinase-1 (TIMP-1) were measured by reverse transcription polymerase chain reaction.
方法应用逆转录酶-多聚酶链反应(RT - PCR)方法，检测了83例食管癌和贲门癌组织及28例患者45枚淋巴结中MRP基因的表达，并与相应癌旁组织进行对照分析。
Methods RT-PCR was applied to study expression of MRP gene in tumor tissues from 83 cases of esophageal and cardiac carcinoma, and 45 lymph nodes from 28 patients.
采用半定量逆转录多聚酶链反应(RT - PCR)检测局部内皮素系统ET - 1、ETAR、ETBR及ECE的基因表达。
The gene expression of ET-1, ETAR, ETBR and ECE was evaluated by semi-quantitative reverse transcription polymerase chain response (RT-PCR).
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