目的探讨左旋多巴治疗帕金森病诱发羟自由基增高的机制与防治的药物。
Objective To investigate the mechanism and prevention of increasing hydroxyl radical induced by L-DOPA treatment in Parkinson's disease.
提取物中总黄酮和多酚类物质的含量与清除羟自由基能力有密切关系。
There are close connection between the hydroxyl radical scavenging activity and flavonoids content or polyphenols content.
方法分别采用不同黏度与用量的羟丙甲纤维素(HPMC),不同主药粒径与稀释剂,不同工艺制备盐酸曲马多缓释片。
METHODS Different particle size of tramadol hydrochloride, viscosity grades and the amount of HPMC, additive content and process were used to prepare tramadol hydrochloride sustained release tablets.
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