指巧言谄媚、不行正道的人。《汉书·元帝纪》：“咎在朕之不明，亡以知贤也。是故壬人在位，而吉士雍蔽。” 颜师古 注引 服虔 曰：“壬人，佞人也。”
目的建立体外培养的正常人表皮黑素细胞系，检测壬二酸对人表皮黑素细胞和鼠黑素瘤B16细胞黑素合成的影响。
Objective To establish human normal melanocytes cell line in vitro and observe the effects of Azelaic acid on the pigment production of the epidermal melanocytes and B16 cells.
壬二酸抑制人表皮黑素细胞和鼠黑素瘤B16细胞的酪氨酸酶活性，细胞黑素合成减少，而且具有浓度依赖性。
The melanin synthesis and tyrosinase activity of human epidermal cells and murine B16 melanoma cells were inhibited by Azelaic acid in a dose-dependent manner.
测定壬二酸对人表皮黑素细胞和鼠黑色素瘤B16细胞酪氨酸酶活性及黑素含量变化观察壬二酸的脱色素作用。
The influence of azelaic acid on melanin synthesis and tyrosinase activity of human melanocytes and murine B16 melanoma cells were studied.
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