具有制作假体基因的能力，标志着个体基因工程在传统的基础上有了重要的进步。
The ability to make prosthetic genomes marks a significant advance over traditional genetic engineering of individual genes.
本周达成的协议转向以现货价为基础的季度合约，这标志着已持续40年的年度基准合 约体系寿终正寝。
The agreement this week to move to quarterly contracts based on spot prices marks the end of the annual benchmark system that has lasted 40 years.
那次地震城中基础设施业已受损，又历经其后连续余震，在本次地震中许多新建筑也倒塌了——包括了该市标志性建筑圣公会教堂的塔顶。
With the city's infrastructure weakened then, and during the run of aftershocks since, many of its newer buildings toppled this time-as did the spire of Christchurch's iconic Anglican cathedral.
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