少数的牙源性角化囊肿是多发性,并且这些病例的50%合并有基底细胞痣综合症。
A minority of odontogenic keratocysts are multiple and 50% of these cases will have associated basal cell nevus.
方法采用PCR - SSCP筛查与DNA直接测序的方法对12例okc进行PTCH基因突变的检测,其中2例为痣样基底细胞癌综合征(NBCCS)相关okc, 10例为散发okc。
Methods PCRSSCP and DNA sequencing were used to analyze the PTCH gene mutations in 12 OKCs, including 10 sporadic and 2 nevoid basal cell carcinoma syndrome (NBCCS) associated OKC.
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