新达尔文主义认为这种不完整性，从根本上来自于有关的物种成员的基因组突变。

Neo-Darwinism suggests that such imperfections arise primarily from mutations in the genomes of members of the species in question.

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然而通过对她的整个基因组测序发现，一个编号为TP53的基因发生了突变，而这正促使了肿瘤的形成。

Full genome sequencing, however, revealed she had a mutation in a gene called TP53, which suppresses tumor formation.

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Plexxikon之所以能开发出这种药物，是因为研究人员利用基因测序仪绘出了黑色素瘤细胞的基因组，并发现了一个关键的突变。

Plexxikon was able to develop the drug because researchers using a gene sequencing machine had mapped the genomes of melanoma cells and found a key mutation.

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