嘌呤受体(Purinergic receptors)是一个跨膜受体家族,其可以被细胞外核苷和核苷酸激活。这一大的受体家族可以分为P1和P2受体两大类。
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而ATP作为一种神经递质,它的生物学作用是由其受体介 导的,于是1978年Bumstock提出了“嘌呤受体(Purinoceptor)’’或“嘌呤能受 体(Purinergicreceptor)",并将其分为腺苷作用的P1受体(腺苷受体)和ATP 及其类似物作用的P2(腺嘌呤核苷酸...
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Purinergic receptors are divided into two major classes P1 and P2.
嘌呤受体分为P1和P2两大类。
参考来源 - P2X7受体介导的小胶质细胞形态变化和受体表达的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
由ATP携带的信息接收细胞表面的特定受体,我把它称为嘌呤受体,因为ATP属于嘌呤的一种。
The messages carried by ATP are received on the surface of cells by specific receptors, which I termed purinoceptors, because ATP belongs to a group of chemicals known as purines.
但是,如果他的研究成果经得起别人的推敲,那么寻找另一个嘌呤受体阻滞剂将会是值得一试的途径。
But if his work stands up to the scrutiny of others, then looking for another purine-receptor blocker would surely be a worthwhile endeavour.
嘌呤能P 2x7受体激活可导致大鼠视网膜神经节细胞死亡和胞内钙离子浓度升高。
The activation of purinergic P2X7 receptor can cause rat retinal ganglion cell death and the increase of intracellular calcium.
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