咪达普利化合物是从乙酸乙酯-n-己烷得无色结晶,熔点139-140℃。[α]D20-71.7°(C=0.5,乙醇),化学名为(-)-(4S)-3-[(2S)-2[(1S)-1-乙氧羰基-3-苯丙基]氨基丙酰基]-1-甲基-2-氧代咪唑啉-4-羧酸。临床上属于血管紧张素转化酶抑制剂,前体药物,用于高血压。
咪达普利对中国高血压病人的疗效及安全性观察_医网打尽文献搜索 关键词 咪达普利;高血压病 [gap=1380]Key words imidapril;essential hypertension
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But the expression of these sign shows no difference between imidapril treated group and valsartan treated group(P>0.05).
而各检测指标在咪达普利组与缬沙坦组中的表达无差别(P>0.05)。
参考来源 - 咪达普利、缬沙坦抑制动脉粥样硬化的作用及其机制·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:建立盐酸咪达普利及片剂含量测定方法。
OBJECT To establish a method for determining the content of Imidapril Hydrochloride and Imidapril Hydrochloride tablets.
咪达普利抑制心房纤维化可能还与影响CTGF途径有关。
Imidapril inhibit atrial fibrosis maybe also related to affect the CTGF way.
结论:咪达普利和贝那普利降低外周动脉压和中心动脉压一样有效。
CONCLUSION: Imidapril and benazepril are both similarly effective in the reduction of the peripheral blood pressure and the central blood pressure in the treatment of hypertension.
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