中文名称:吡美莫司;匹美克莫司 英文名称:pimecrolimus CAS NO.: 137071-32-0 分子式: C43H68ClNO11 分子量: 810.45 密 度: 1.19 含量:92%以上 包装:5克/包 标准:企业标准 产品类别:一种抗炎症药物
...免疫调节药物 对于那些对温和的激素软膏无效或需要长时间使用激素的儿童就需要考虑使用局部免疫调节药物,如Elidel(吡美莫司)、Protopic(他克莫司)是两个可以用于儿童的产品。
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吡美莫司乳膏 Pimecrilimus Cream
According to the patent literature, we improved and simplified the response route, and reduce costs; pimecrolimus yield: 42.1%, the purity > 96%, mp 135.2-136.1℃, according to the data above, the product is confirmed to be pimecrolimus.
对专利文献方法进行了改进,提高了收率,降低了成本;吡美莫司的总收率42.1%,纯度>96%,熔点为135.2-136.1℃,与文献报道相符。
参考来源 - FK520的分离及其衍生物的合成·2,447,543篇论文数据,部分数据来源于NoteExpress
该小组也报道指出停用吡美莫司乳膏并不会导致随访期患者皮肤症状反弹。
Stopping pimecrolimus cream did not lead to a rebound of skin symptoms in most of the patients who entered the follow-up phase, they also report.
与预料一样,吡美莫司耐受性良好,该研究小组指出,吡美莫司没有严重的副作用。
As expected, pimecrolimus was well tolerated, the team reports, noting that there were no drug-related serious adverse effects.
吡美莫司治疗皮质类固醇激素诱导的口周皮炎患者尤为有效。吡美莫司治疗的患者生活质量改善比对照组多。
Pimecrolimus was most effective in patients with corticosteroid-induced POD. Pimecrolimus-treated patients reported greater gains in quality of life than control-treated patients.
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