古拉定（注射用还原型谷胱甘肽钠），适应症为用于酒精及某些药物(化疗药、抗肿瘤药、抗结核药、、精神抑郁药、抗抑郁药、扑热息痛)，导致的中毒的辅助治疗，用于酒精、病毒、药物及其他化学物质导致的肝损伤的辅助治疗，用于电离射线所致治疗性损伤的辅助治疗，用于各种低氧血症的辅助治疗。
目的：初步验证古拉定(国产注射用还原型谷胱甘肽)对酒精性肝病的疗效。
Objective: To study the efficacy of domestic reduced glutathione vial for injection in comparison with imported Gluthion in treatment of chronic alcoholic liver disease (CALD).
方法SD大鼠，随机分为对照组、模型组、川芎嗪大剂量组、川芎嗪小剂量组、古拉定组。
METHODS The SD rats were randomly divided into control group, model group, high-dose tetramethylpyrazine group, low-dose tetramethylpyrazine group and GSH group.
目的：研究古拉定、川芎嗪、丹参对6-羟基多巴胺（OHDA）处理后大鼠的黑质多巴胺（DA）神经元及纹状体细胞外液DA的影响。
Objective:To study the effect of glutathione (GSH), Ligustrazine and Salvia miltiorrhiza on dopamine (DA) and its metabolites of corpus striatum and DA neurons in rats injected with 6-OHDA.
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