我们知道是什么原因导致了野生老虎数量的下降，这些原因就是：非法偷猎；非法野生动植物贸易；变更用途、侵占和土地退化导致的栖息地丧失。
We know what is causing the decline in Numbers of wild tigers: illegal poaching; illegal wildlife trade; loss of habitat through conversion, encroachment, and land degradation.
然而，一些厂商宣传它们的可视化建模工具的用途，但是没有强调将模型与实现过程中的设计决策和变更保持同步的重要性。
However, some vendors promote the use of their visual modeling tools without emphasizing the importance of keeping models in synch with design decisions and changes during implementation.
组织应当确定医疗器械的功能、操作、可用性、安全性和适当的法规要求和它的预期用途变更的重要性。
The organization shall determine the significance of the change to function, performance, usability, safety and applicable regulatory requirements for the medical device and its intended use.
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