变应性鼻炎和哮喘等呼吸道变应性炎症存在共同的炎症反应机制。
Allergic inflammation of respiratory airway, including allergic rhinitis and asthma, has the same pathogenesis of inflammation reaction.
目的：在肠道菌群失调小鼠模型上采用屋尘螨变应原诱导气道变应性，建立一种新的变应性气道反应模型。
Objective:To establish the intestinal microflora imbalance mouse model to construct a novel allergic airway response model induced by dermatophagoides pteronyssinus allergens.
结论：西替利嗪治疗常年变应性鼻炎与阿司咪唑比较具有起效快、不良反应少的特点。
CONCLUSION: the effect of cetirizine in treating perennial allergic rhinitis is faster and the adverse reaction is less than those of astemizole.
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