原发性胆管结石是指原发于肝内的外胆管内有结石病，是最常见的胆道系统疾病。结石阻塞胆管引起胆汁淤滞，继发细菌感染而导致急性胆管炎发生。
即原发性肝胆管结石 primary intrahepatic stone
原发性胆总管结石 primary choledocholithiasis
原发性肝内胆管结石 primary intrahepatic stones
与原发性肝内胆管结石 primary intrahepatic stones
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原发性胆管结石是相对于继发性胆管结石的一个概念，指发生于肝内外胆管而非继发于胆囊的结石。
Primary bile duct stone, a notion relative to secondary common bile duct stone that come from gallbladder.
原发性肝内胆管结石是我国的常见病，由于该病并发症多，手术难度大，故被认为是胆道良性疾病中一种难治的疾病。
Primary intrahepatic stone is a common disease in China. It is difficult to treat this benign biliary tract disease because it has many complications and the surgery is difficult.
文中将从胆汁成分的失衡、感染、胆汁中的蛋白及大分子及细胞代谢四个方面对原发性肝内胆管结石的成因加以综述。
This article reviewed the cause of primary intrahepatic stone from four aspects: imbalance of bile components, infection, bile protein, and macromolecular and metabolism of the cells.
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