It verified further that the cadmium interfered the transcription of gene which promotes ovarian follicle cell's developing. It might be one mechanism of the cadmium’reproduction toxicity.
6.应用半定量RT-PCR法检测了鸡卵巢内FSHR、LHRmRNA表达水平,结果表明镉能够降低卵巢FSHR、LHRmRNA的表达水平,进而抑制卵泡发育,进一步证实镉能够干扰促进卵泡细胞发育基因的转录,这可能是镉的生殖毒理机制之一。
参考来源 - 亚慢性镉中毒致鸡卵巢损伤机制的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
前泡膜细胞被募集到原始卵泡周围，原始卵泡发育并向初级卵泡转化。
The germ line cysts break apart into individual cells and become packaged into primordial follicles.
在有腔卵泡，随着卵泡发育变大，FSHR阳性细胞逐渐减少，LHR阳性细胞逐渐增多。
In antral follicle, FSHR cell amount gradually decreased and LHR cell increased accompanied by follicle development.
文章主要围绕支持细胞中促卵泡素信号途径，及其对细胞发育过程中相关基因表达的影响等方面进行了综述。
In this review, we discussed FSH signaling pathways and the gene expression changes during Sertoli cell development and spermatogenesis.
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