如果SRY基因缺失,即使胚胎是男性的,其性腺也会发育成卵巢。
If SRY is missing, the gonad develops into an ovary, even if the embryo is male.
结论:本文的研究结果提示X染色体长臂末端可能是卵巢早衰的特异性基因区段并与X染色体末端端粒的缺失有关。
Conclusion: The result showed that terminal deletion of Xq and telomeric deletion of X chromosome were important factors of premature ovarian failure.
他说:“这些卵巢切除的动物是研究绝经的理想模型,因为卵巢产生的雌激素的缺失模仿了绝经女性雌激素的自然减少。”
He said, "These ovariectomized animals are a good model for study of the menopause as the loss of oestrogen from the ovaries mimics the natural reduction in oestrogen seen in menopausal women."
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