加重；加剧；恶化加重恶化的行为或被加重、恶化的状态。

The act of aggravating or the state of being aggravated.

youdao

结论：糖尿病是脑缺血再灌注损伤重要因素之一；内皮素- 3和星形胶质细胞激活可能是糖尿病小鼠神经细胞损伤加重恶化的机制之一。

CONCLUSION: Diabetes is one of the important causes of cerebral ischemia reperfusion injury, and et 3 and activated astrocytes may worsen the neural injuries in diabetic mice.

youdao

但健康改善趋势不是注定的，事实上，如果不加重视，健康状况可能会迅速恶化。

But trends showing improved health are not foreordained. In fact, without attention health can decline rapidly.

youdao

And indeed, he got progressively and then rapidly deteriorated at that point.

实际上，在那个时候，他的病日益加重,并随后迅速恶化。

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