有关选择性剪接的调控机制是功能基因组时代的重要前沿问题之一。
Problems about mechanisms control alternative splicing is a leading research endeavors in functional genome era.
虽然在实验室条件下人们可以非常精确地对DNA进行剪接，但一个外源基因导入植物体后，对整个植物基因组的影响人们尚不能完全预测和控制。
We can cut DNA exactly in the lab, but we cannot predict and control the effects on the whole plant genes after the "outside" genes which are transplanted into the plant.
我们在一组人类基因中发现了与剪接结果相关的独特的组蛋白修饰特征，及组蛋白导致剪接位点转换的调节。
We found distinctive histone modification signatures that correlate with the splicing outcome in a set of human genes, and modulation of histone modifications causes splice site switching.
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