结论酒石酸美托洛尔片单剂量和多剂量给药后，安全性良好。
Conclusion There are good safety after administrating single and multiple oral dose of metoprolol tartrate.
目的建立单室模型药物血管外多剂量给药的吸收和清除药动学的残数法计算方法。
Objective To establish a feathering method for processing the pharmacokinetic parameters of mono-compartment drugs administered by non-parenteral route by repeated doses.
对病例加大锑剂用量，改传统用药为按不同公斤体重增大锑剂总剂量给药可降低复发率。
The recurrence rate could be reduced by increasing the dosage of antimonials according to patients' body weight. Increasing the dosage of antimonials is still effective to recurring cases.
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