就神经氨酸酶抑制剂而言，有一些重大的限制因素，主要是生产能力有限，同时，在许多国家，其价格高得难以负担。
For the neuraminidase inhibitors, the main constraints - which are substantial - involve limited production capacity and a price that is prohibitively high for many countries.
但是，近期在美国和墨西哥发现的病毒对抑制剂很敏感，却对amantadanes有抵抗力。
The virus that was currently detected in the us and Mexico is susceptible to neuraminidase inhibitors but resistant to amantadanes.
证明杂质在最后的制剂中可能会引起降解，并导致稳定性有问题。
It has been demonstrated that impurities in a finished drug product can cause degradation and lead to stability problems.
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