结果：在404 166 人的追踪期间， 1081个报告了具有征候的胆结石疾病， 885 必需作胆切除术。

RESULTS: During 404 166 person-years of follow-up, 1081 subjects reported symptomatic gallstone disease, of whom 885 required cholecystectomy.

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药物超敏反应综合征是一种具有特异征候的重症药疹。

Drug-induced hypersensitivity syndrome (DIHS) is a severe drug eruption with characteristic symptoms.

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