lagosin 由玫瑰藤黄链霉菌(Streptomyces roseoluteus)产生的五烯抗生素。为黄或白色结晶。于乙醇、吡咯中溶解良好。微溶于水、乙醚、乙烷。中性。具有抗肿瘤活性。
目的比较研究以链脲佐菌素与四氧嘧啶作为诱导剂建立兔1型糖尿病模型的效果及特点。
Methods The STZ and ALX of different concerntrations were injected into the rabbits through auricle edge vein and abdominal cavity to induce the type 1 diabetes models.
方法通过静脉注射致病剂量链脲左菌素（STZ），诱发兔高血糖，制备2型糖尿病兔模型；
Methods Rabbit models with type 2 diabetes were induced by intravenous injection of streptozotocin (STZ).
抑制豚鼠旧结核菌素皮肤迟发超敏反应、兔E玫瑰花结形成及淋巴细胞转化；
In guinea pigs, it also inhibited OT skin test, RE rosette formation and lymphocyte transformation.
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