免疫监视功能(immunologic surveillance):正常情况下机体免疫系统能把少量突变细胞加以消灭清除,防止癌变的发生,也能防止病原微生物的持续性感染。
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DC数量减少和功能缺陷,也是肿瘤细胞逃避机体免疫监视的机制之一。
The decreased infiltration and functional deficiency of DCs may also contribute to tumor cells evading from surveillance of immune system.
一些肿瘤细胞譬如T细胞淋巴瘤el 4细胞等也表达CD 47分子,抑制机体吞噬细胞功能逃逸免疫系统的免疫监视。
Some tumor cells (e. g., t lymphoma EL4 cells) express CD47 and block phagocytosis of phagocytes in order to escape from the surveillance of immune system.
小胶质细胞是中枢神经系统常驻细胞,行使支持、营养、免疫监视等多种功能。
Microglia are resident immune cells of the CNS, which play the roles of sustaining, nourishing and immune surveillance.
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