Preliminary studies on SAR of hypnotic activity revealed that the hypnotic activities and irritations of N-substituted oleamide derivatives and N-oleoyl-N? -substituted piperazine derivatives are both lower than those of their mother substances S01 and S07.
对催眠活性的试验结果显示：油酰胺和油酰哌嗪的氮原子被烷基或芳基取代后，催眠活性均较母体化合物降低，同时给药刺激性也降低。
参考来源 - 油酰胺衍生物的合成及催眠活性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
因其有独特的药理活性如：活血散瘀、理气止痛、镇静和催眠、抑制胃液分泌及胃酸等功效而广泛受到国内外学者的关注。
Because of its unique pharmacological activities such as blood stasis, sedation and hypnosis, inhibition of gastric acid secretion, scholars have been interesting about the plant.
方法采用镇静、催眠实验比较生、炒酸枣仁的药理活性，采用RP HPLC梯度洗脱法对生、炒酸枣仁进行化学成分的全成分分析。
Methods Their activity tests were comparatively carried out by the sedative and hypnotic experiments and the total components were analyzed by RP-HPLC.
应用推荐