共价催化涉及底物与活性位点中的残基或与辅因子形成瞬时共价键。
Covalent catalysis involves the substrate forming a transient covalent bond with residues in the active site or with a cofactor.
酪氨酸576和酪氨酸577处于激酶结构域的激活环，这些残基的突变减弱FAK的催化活性（6）。
Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).
目的研究和探讨大鼠血红素加氧酶鄄1（RHO鄄1）中保守的碱性氨基酸精氨酸残基和赖氨酸残基对该酶催化功能的影响。
Objective To study the catalytic function of conservative basic amino acid arginine residue and lysine residue on rat heme oxygenase-1(RHO-1).
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