来曲唑（Letrozole），别名 芙瑞，是一种白色或类白色粉末的化学品。化学名称1-[双(4-氰基苯基)甲基]-1,2,4-三氮唑;4,4'-(1 H-1,2,4-三唑-1-基亚甲基)-双苯腈，分子式为C17H11N5，分子量为285.31。是新一代芳香化酶抑制剂，为人工合成的苄三唑类衍生物，来曲唑通过抑制芳香化酶，使雌激素水平下降，从而消除雌激素对肿瘤生长的刺激作用。用于乳腺癌的内分泌治疗。
来曲唑 Letrozole ; Femara ; Lelrozol ; Letrozol Tablets
来曲唑片 Letrozol Tablets ; LelrozolTablets ; Letroz ; Lelroz
来曲唑杂质A Letrozole impurity ; Letrozole Related Compound
来曲唑杂质C Letrozole impurity
来曲唑杂质B Letrozole impurity
来曲唑中间体 Dicyanobenzophenone
来曲唑杂质 Letrozole impurity
芳香化酶抑制剂来曲唑 aromatase inhibitor letrozole
曲来唑 Letrozole
曲来唑的化学合成 Letrozole
目的：评价来曲唑在生育与妇产科临床应用情况。
OBJECTIVE: To evaluate the use of letrozole in reproduction and clinical obstetrics gynecology.
本文综述了来曲唑的合成方法以及临床研究进展。
The advances in the research of the synthesis and clinical studies of Letrozole were reviewed in this paper.
来曲唑可用于连续5年、每天服用三苯氧胺的绝经后妇女。
Letrozole may be used for postmenopausal women who have completed 5 yr of daily tamoxifen.
应用推荐