昏暗的光线使眼睛很难受。

The grey light was hard on the eyes.

《柯林斯英汉双解大词典》

接近华氏100 度的高温使他们感觉热得难受。

They sweltered in temperatures rising to a hundred degrees.

《柯林斯英汉双解大词典》

不要让自己难受，那就是使你烦恼的一切。

Spare thyself discomfort, an' that is all that troubles thee.

youdao

In particular, what happens is he is given a drug that makes him violently ill, extremely nauseous.

具体情况是这样的，在治疗过程中，心理学家喂他吃一种药,使他变得难受至极，特别恶心。

耶鲁公开课 - 心理学导论课程节选