他父亲的去世使他蒙受巨大的损失。

He has sustained a great loss by the death of his father.

《新英汉大辞典》

相比之下，成本-效益分析则通过比较不同人群的获益和损失，提出改变规则的对策，使收益大于损害。

Incontrast, cost-benefit analysis weighs the gains and losses to differentindividuals and suggests carrying out changes that provide greater benefitsthan harm.

youdao

这种损失反过来又会对社会造成伤害，使增长率降低，就业减少。

That loss in turn hurts society in lost growth and in lost job creation.

youdao

You would be exploiting insider information and you would be victimizing the outsiders.

利用内幕消息获取利益,就会使局外人承受损失

耶鲁公开课 - 金融市场课程节选