KIR2DL与相应的配体HLA-C结合后传递抑制信号,使NK细胞对靶细胞的杀伤作用被抑制。
KIR2DL can bind the classical HLA-C antigen, and produce inhibitory signals which can inhibit the cytotoxicity of NK cell.
它显然是通过抑制神经递质的释放来做到这一点的。神经递质是一种将神经冲动从一个神经元传递到另一个神经元的化学物质。
It apparently does this by inhibiting the release of neurotransmitters, chemicals that carry nerve impulses from one neuron to the next.
但当抑制性T细胞想要阻止这一行为时,他们被传递了相同的抗原,开始杀死抗原呈递细胞。
But when the weak t cells that want to stop the disease are presented with those same antigens, they kill the APC.
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