结果:RT-PCR可在心脏、肝脏、脾脏、肾脏以及脑组织内检测到病毒核酸,透射电镜下可在肝细胞胞浆内观察到形态典型的病毒粒子。
R esu lts:The nuc le ic ac id of CCHF virus could be detected in the hearts, livers, spleens, kidneys and brains of the infected suckling mice by the RT-PCR.
本发明还公开了检测G蛋白偶联受体核酸序列中的突变的诊断方法以及检测受体的可溶形式的改变水平的诊断方法。
Also, disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.
本发明还公开了检测PAF受体核酸序列中的突变的诊断方法以及检测从宿主获得的样品中受体的可溶形式的水平的诊断方法。
Also disclosed are diagnostic methods for detecting a mutation in the PAF receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.
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