结论构建了人瘦素的哺乳动物细胞表达载体，并成功地在COS 7细胞中获得重组人瘦素的分泌表达。

Conclusion Cloning and expression recombinants of human leptin are obtained and secretive recombinant human leptin is successfully expressed in COS-7 cells.

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当人或啮齿类动物体重下降10%或更多时，瘦素的水平就会急剧下降，引发一连串的生理变化，促使体重回升。

When humans (and rodents) lose 10% or more of their body weight, leptin falls rapidly and sets off a cascade of physiological changes that act to put weight back on.

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胖人的血液中的瘦素含量异常的高。

Obese people have been found to have an abnormally high level of leptin in their bloodstream.

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