这是因为大流行病毒比预料传播更为迅速，即使对它有普遍免疫性，季节疫苗的抗体与它也没有交叉作用。
This was because the pandemic virus spread faster than would be expected if there were widespread immunity to it, and because antibodies to the seasonal vaccine do not cross-react with it.
在过去的一年半中有一些进展，因为人们能够识别可交叉反映的单克隆抗体——能够预防多个变种的抗体。
There was some advance in the last one and a half years in that people were able to identify cross-reactive monoclonal antibodies-antibodies that can be protective against a variety of strains.
抗体对蛋白质的四级结构产生应答，因此它们对同种异型抗原发生交叉反应的能力较弱。
Antibodies respond to the quaternary structure of proteins so their potential to cross-react with an alloantigen is very low.
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