除非二线治疗的价格大大降低，否则，预算限制将妨碍治疗方案的实施。

Unless prices for second-line regimens fall significantly, budgetary constraints may put treatment programmes at risk.

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而在成都，大连等二线三线城市的消费者也将快速地跟上国际潮流。

And consumers in the second - and third-tier cities like Chengdu and Dalian will move with lightning speed to catch up with international trends.

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债市方面，西班牙周四将标售五年期公债，而投资者仍在担心欧元区二线国家局势，尤其是希腊有可能进行债务重组。

In bond markets, Spain auctions five-year debt on Thursday as investors continue to fret about the euro zone periphery, in particular the possibility of Greek debt restructuring.

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