是由睾丸分泌的一种类固醇激素。是人体内主要的雄激素,与男性第二性征的发育有关。睾酮作为一种激素原,在芳香化酶的作用下可转变为17 β-雌二醇。性状:结晶。一种促蛋白质合成的甾类化合物。分子式:C19H30O2 分子量:290.44。 中文又称:双氢睾酮。英文名:Dihydrotestosterone,简称DHT。
As a 5α-2 reducing enzyme inhibitor, it can decrease the level of dihydrotestosterone (DHT) significantly. The inhibition of finasteride may cause serum DHT decreasing by 60%-80%, and prostatic DHT decreasing by 90% above.
它作为一种Ⅱ型5α-还原酶抑制剂,能显著降低二氢睾酮(DHT)水平。
参考来源 - 非那甾胺缀合物的合成及生物活性·2,447,543篇论文数据,部分数据来源于NoteExpress
二氢睾酮也宣布为双氢睾酮。
在男性和女性中,二氢睾酮对男女性征的发育都有重要作用。
Naturally found in males and females, DHT plays a key role in development of male characteristics for both men and women.
一些男性或者女性,具有二氢睾酮攻击毛囊的遗传性倾向,特别是攻击头顶的毛囊。
Some men or women, however, have a genetic propensity for DHT to "attack" hair follicles, especially those on the top of the head.
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