事实已经证明很难开发减肥药，只有少量药物进入市场。
Obesity drugs have proved difficult to develop, and only a few have entered the marketplace.
事实已经证明，过去几年对大部分退休帐户来说都是艰难的。
The past couple of years have proven tough for most retirement accounts.
事实已经证明可能对这种基因遗传进行修补，并产生了令人吃惊的结果。
It has already proved possible to tinker with this genetic inheritance, with startling results.
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