研究者发现,敲除FucM基因——这个基因影响了雌激素的水平,进而使大脑受到影响——使得雌性老鼠在长大过程中的行为仿佛就像雄性一样。
Researchers found that disabling the FucM gene - which influences the levels of oestrogen to which the brain is exposed - caused the mice to behave as if they were male as they grew up.
他们发现这种敲除基因的小鼠骨髓中的淋巴细胞较正常鼠少50%,产生特异免疫细胞的胸腺较正常鼠少80%。
They found that the knockout mice had 50 percent fewer lymphocytes in their bone marrow and 80 percent fewer in their thymus, a collection of glands that helps produce specialized immune cells.
在AEP基因敲除的小鼠实验中,该药物及人为中风所导致的DNA损伤与脑细胞死亡均比非基因敲除小鼠程度减轻。
In mice genetically engineered to lack AEP, both the drug and an artificial stroke resulted in reduced DNA damage and less brain cell death than in regular mice.
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