成骨不全症 成骨不全症（Osteogenesis Imperfecta）指的是一种因先天遗传性缺陷，而引起第一型胶原纤维病变，造成骨骼强度耐受力变差而容易脆弱骨折的疾病。
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目的总结帕米膦酸钠在成骨不全症中的应用经验。
Objective To summarize the experience of pamidronate for osteogenesis imperfecta.
结论帕米膦酸钠对成骨不全症有较好疗效，但需更多病例观察。
Conclusion Pamidronate therapy has a positive effect on patients with osteogenesis imperfecta, while this still remains to be demonstrated in more patients with osteogenesis imperfecta.
方法对2007年我院收治的2例成骨不全症的治疗进行回顾分析。
Methods To review the effect of intravenous pamidronate therapy on two patients with osteogenesis imperfecta in 2007.
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