You feel desperate because you know that if you crash into these five workers, they will all die.

你此时极度绝望,因为你深知,如果电车撞向那五名工人，他们全都会死。

耶鲁公开课 - 公正课程节选

Thank you. I just feel like in the situation that desperate, you have to do what you have to do to survive.

谢谢，我只是认为,在那样的绝境下，为了生存，你不得不那样做。

耶鲁公开课 - 公正课程节选

Do you see that word "throbs"? " A desperate honesty that throbs through his confession."

你们看到那个字了吗，悸动“,他的忏悔被绝望的虔诚悸动着“

耶鲁公开课 - 1945年后的美国小说课程节选

Are you desperate to find out how your graduate school has fared?

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Concentrating on lessons when you are desperate for the bathroom is hard on anyone.

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You become desperate to find a life for yourself and your family.

FORBES: Magazine Article