It was the worst week of my life. It was ghastly.

这是我一生中最糟糕的一周。令人讨厌。

《柯林斯英汉双解大词典》

I am having the worst week of my life!

这是我一生中最倒霉的一周。

youdao

This has been the Dow's worst week ever.

这是道琼斯指数有史以来最糟糕的一周。

youdao

The American media has decided that President Obama has just had his worst week ever.

BBC: Obama's worst week?

Overall, global equities had the worst week since the middle of the financial crisis.

FORBES: The Week Ahead: Waiting for QE3

The first week hatching StrawberryFrog, my own ad agency, was the worst week of my life.

FORBES: How To Start A Successful Ad Agency