Loved ones, family breakdown, love, serious physical illness, learning and work difficulties and setbacks and other stressful events are easy to cause people's self-esteem and cause this disease.

亲人死亡、家庭破裂、失恋、严重的躯体疾病、学习和工作中的困难和挫折等应激事件容易使人自尊心受到打击而诱发此病症。

youdao

Now I meet with fewer difficulties in my work.

现在我工作中困难少些了。

《新英汉大辞典》

The work of Wildman and Niles suggests the importance of recognizing some of the difficulties of instituting reflective practice.

怀尔德曼和奈尔斯的工作表明，认识到建立反思实践的某些困难的重要性。

youdao

"This is a rough-and-tumble place and it's nice to come back to two people who care about me, who care about my success, who care about the difficulties I might be having either at work or at home and just to have two friends who are a sounding board."

VOA: standard.2010.08.07

Analysts said the scale of Hon Hai's operations and the tedious nature of the work mean difficulties for the company likely will continue.

WSJ: Hon Hai Riot Highlights Squeeze on Chinese Manufacturers

It will take time to work through the difficulties in our markets and our economy, and new challenges will continue to arise.

FORBES: Magazine Article

"It will take time to work through the difficulties in our market and our economy and new challenges will continue to arise, " he said.

BBC: US Fed announces $800bn stimulus