You should persist in your dream no matter what difficulties you meet.

无论你遇到了什么困难，你都应该坚持自己的梦想。

youdao

No matter what difficulties we meet, we should try to face them instead of running away from them.

无论遇到什么困难，我们都应该努力面对，而不是逃避。

youdao

A young couple have no idea of what difficulties may confront them in their work, their family life and even from society.

年轻夫妇对工作、家庭生活及社会中可能会出现的困难估计不足。

youdao

But guess what? In the last decade weve been able to produce, in spite of all these difficulties, health workers in Mogadishu, in a hospital in Banadir University.

VOA: standard.2009.12.05

A lot of sciences rest on data that is flawed in some ways because of the difficulties in assessing what people eat.

许多依赖数据的科学常识是有瑕疵的,由于评估人类所吃食物非常困难

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

They usually know better than anyone what their difficulties are.

NEWYORKER: Personal Best

"Both these men were well equipped with crampons and ice axes and they got into difficulties in what are really still very difficult conditions, " he said.

BBC: North West Wales

The trestle points to the difficulties of determining what relics constitute rock lore and ought to be preserved.

WSJ: For R.E.M. Fans, Tunes May Linger But Trestle Faces Day of Reckoning