In able-bodied people, these "walking circuits" spring into action when they receive a signal from the brain, but if the spinal cord is damaged, the message from the brain never arrives.
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A team led by Courtine used drugs known as serotonin agonists to awaken the walking circuits in paralysed rats whose spines had been severed.
据刊登在《自然—神经学》（Nature Neuroscience）杂志上的一份报告所述，由库尔蒂纳带领的研究小组对脊髓完全受损的瘫痪老鼠进行了实验，实验中采用叫做血清素致效剂（serotonin agonist）的药物，来唤醒瘫痪老鼠的步行回路。
Courtine said the group is eager to begin human trials, but first needs to develop implantable electrodes to stimulate the walking circuits in patients' spines.
库尔蒂纳表示，该研究小组迫切希望开始人体试验，但首先需要开发便于刺激患者脊椎中步行回路的植入式电极。
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