But in the past,the majority of the researches about TRIM5αwere finished by gene transfection. For example,TRIM5αgene was conveyed into the cells by liposome or viral vector.
以往关于TRIM5α的绝大多数研究,主要围绕在基因水平上进行的,例如,通过脂质体、病毒载体等结构将TRIM5α基因转运进入细胞使之大量表达,从而改变细胞的表型。
参考来源 - 重组人TRIM5α基因嵌合体的构建、表达纯化及其体外抑制HIVCationic liposome has been extensively used as a non-viral vector for the delivery of reporter and therapeutic genes in vitro and in vivo.
阳离子脂质体作为非病毒载体已经在体内、外实验中广泛用来递送报告基因和治疗基因。
参考来源 - DOTAP/DOPE、壳聚糖作为基因载体的应用研究·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
Recently, researchers pay more and more attention to non-viral vector.
近年来,非病毒载体的研究越来越受到重视。
Vector retargeting is one of the important strategies on viral vector targeting.
载体的靶向策略很多,载体重靶向就是其中重要的一种。
Conclusion: the established viral vector AdmlcGFP allows heart specific expression of a foreign gene.
结论:构建的心肌特异性表达腺病毒载体可使外源基因在心肌细胞内特异性表达。
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