The classification, mechanism and application of VEGF and VEGFR in anti-tumor therapy are reviewed.

本文综述了VEGF及其受体的分类、作用机制及在抗肿瘤治疗中的应用。

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Angiogenesis induced by VEGF and its receptor (VEGFR) play a critical role in tumor growth and metastasis.

VEGF及其受体介导的肿瘤血管新生在肿瘤的生长和转移中具有重要的作用。

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Result: The expression of VEGF and VEGFR was weak in normal nasal mucous, and very strong in nasal polyps.

结果：血管内皮生长因子及其受体在正常鼻粘膜呈弱阳性，在鼻息肉呈强阳性表达。

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Before the advent of the anti-angiogenic VEGFR inhibitors, kidney cancer cure rates were on the order of 5%.

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