Conclusion. We suggest that a genetic variation at the IGF1R gene locus is associated with spinal disc degeneration, in line with the involvement of the IGF1R gene in the cartilage metabolism.

结论：我们认为IGF1R基因位点的遗传突变，主要是与软骨代谢相关的IGF1R基因的受累，与椎间盘退行性变有关联。

youdao

We focused on several key pathways, including nucleotide excision repair, drug transport and metabolism. Both expression and germline DNA variation were evaluated in these key pathways.

由于核苷酸切除修复、药物转运和药物代谢通路在铂金药物功能中的重要性，这篇综述重点总结了这些通路中的基因表达和非癌细胞DNA变异与铂金疗效的关系。

youdao

One example of this is variation in LCT, a gene involved in the metabolism of lactose, a sugar found in milk.

ECONOMIST: Human evolution