V. II: "generation" has the meaning of generational descent spread the word, "second generation" that is the second generation.

二代：“代”有世系相传的辈分的意思，“二代”即第二代。

youdao

It says one dose of the medicine given to mother and child prevents the spread of H.I.V.

VOA: special.2010.05.24

She says the pouch is an important tool for preventing the spread of H.I.V.

VOA: special.2010.05.24

For a dinner or drinks night, a spread collar pairs well with a sport coat or V-neck sweater and looks modern.

WSJ: Guide to Men's Shirt Collars: Which Styles Go With Which Occasions and Flatter the Face