Upregulation of SOD2 can cause an imbalance in antioxidant enzymes, an increase in hydrogen peroxide, and oxidative stress.

SOD2的上调可以致使抗氧化酶的失衡，从而导致过氧化氢(氧化压力)的增加。

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This effect was mediated by transient but dramatic upregulation of the mannose-6-phosphate receptor (MPR) on the tumor cell surface.

这种效果，是肿瘤细胞表面的甘露糖-6 - 磷酸受体（MPR）短暂却显著的表达上调所介导的。

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