The characteristics of the first symptoms are as follows: 41 cases showed upper abdominal pain, accounting for 36%, of whom 16 cases presented with typical peptic ulcer;

本组首发症状特点为：（1）上腹疼痛最多见，41例（36％），其中16例呈典型的溃疡病样规律性。

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Results: the symptoms of these 20 patients were non-specific, upper abdominal pain was most common and hunger pain, abdominal distention, nausea, vomiting, melena being the next.

结果：20例患者的临床表现均无特异性，上腹疼痛最为常见，其次是饥饿痛、腹胀、恶心、呕吐、黑便等。

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In CIC clinical trials, the most common side effect were diarrhea (16% vs 5% placebo), abdominal pain (7% vs 6%), flatulence (6% vs 5%), upper respiratory tract infection (5% vs 4%), sinusitis (3% vs 2%) and abdominal distension (3% vs 2%).

FORBES: FDA Approves New Drug For Irritable Bowel Disorder (Update)