These results are significant because PAH diol epoxides react readily with DNA, induce mutations, and are considered to be ultimate carcinogens of multiple PAH in cigarette smoke.

这些结果具有重要意义，因为多环芳烃二醇环氧化物极易与DNA反应，进而导致变异，因此被视为香烟烟雾中所含多种多环芳烃中最重要的致癌物质。

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"These results are significant because PAH diol epoxides react readily with DNA, induce mutations, and are considered to be ultimate carcinogens of multiple PAH in cigarette smoke, " the study said.

研究认为：“这项结果相当重要，因为多环芳香环氧二醇（PAH diol epoxides）易与DNA反应，引发突变，所以被认为是吸烟产生的众多环芳香烃中最严重的致癌物质。”

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Chemical carcinogens generally require metabolic conversion to some form of "ultimate" carcinogen.

化学致癌物一般需要通过代谢来转换成某种形式的“最终”致癌物。

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